{"id":287,"date":"2021-11-05T20:34:53","date_gmt":"2021-11-05T10:34:53","guid":{"rendered":"http:\/\/dcc.brighterworld.biz\/dcc\/?page_id=287"},"modified":"2024-10-14T18:23:34","modified_gmt":"2024-10-14T08:23:34","slug":"corpus-callosum-disorders","status":"publish","type":"page","link":"http:\/\/ccd.brighterworld.biz\/dcc\/corpus-callosum-disorders\/","title":{"rendered":"Corpus Callosum Disorders"},"content":{"rendered":"<p><section class=\"kc-elm kc-css-472072 kc_row\"><div class=\"kc-row-container  kc-container\"><div class=\"kc-wrap-columns\"><div class=\"kc-elm kc-css-902677 kc_column kc_col-sm-12\"><div class=\"kc-col-container\"><div class=\"kc-elm kc-css-474486 kc_text_block\"><\/p>\n<h5 style=\"text-align: center;\">About Corpus Callosum Disorders (CCD)<\/h5>\n<p>People with a congenital corpus callosum disorder (CCD) are born missing all or part of their corpus callosum, the largest white matter structure in the brain. The corpus callosum is made up of more than 200 million nerve fibres \u00a0and enables communication between the two sides of the brain. It is sometimes described as a bridge or superhighway allowing fast connections between the the hemispheres.<\/p>\n<p>A CCD occurs when the corpus callosum doesn\u2019t form in the usual way. It is diagnosed by MRI or CT scan with four typical presentations:<\/p>\n<ol>\n<li>Complete agenesis \u2013 the corpus callosum did not form at all<\/li>\n<li>Partial agenesis \u2013 only partly formed, anything from small to most of it<\/li>\n<li>Hypoplasia \u2013 the corpus callosum is thinner than usual<\/li>\n<li>Hyperplasia \u2013 the corpus callosum is thicker than usual<\/li>\n<\/ol>\n<p>CCDs occur in <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24477430\/\">1:4000 <\/a>\u00a0live births, which classifies them as a rare disease. The cause may be genetic or something in the environment during pregnancy, for example, a viral infection or exposure to toxins such as alcohol. Sometimes there is no apparent reason. There are more than 350 known genetic causes with scientific research discovering more each year.<\/p>\n<p>CCDs are extremely heterogeneous and can cause cognitive, physical and psychological impacts ranging from mild to severe. There are many associated conditions, for example,\u00a0 intellectual disability, autism, ADHD, OCD, epilepsy and cerebral palsy. Research by <a href=\"https:\/\/www.researchgate.net\/publication\/330714778_The_Neuropsychological_Syndrome_of_Agenesis_of_the_Corpus_Callosum\">Brown and Paul (2019)<\/a> describes the core impacts as: (1) reduced interhemispheric transfer of sensory-motor information; (2) reduced cognitive processing speed; and (3) deficits in complex reasoning and novel problem-solving.<\/p>\n<p>Although there is a growing body of biomedical research about the cause and presentations of CCDs, very little is known about the lives of adults diagnosed with a CCD. This research project, <a href=\"http:\/\/ccd.brighterworld.biz\/dcc\/the-research-program-a-good-life-what-why-and-how\/\">A Good Life<\/a>, aims to work collaboratively with the community of adults with a CCD to understand how they perceive their quality of life and how best to communicate their lived experiences to improve supports for their personal wellbeing.<\/p>\n<p>Click\u00a0<a href=\"https:\/\/ojrd.biomedcentral.com\/articles\/10.1186\/s13023-021-02140-5\">here<\/a>\u00a0to read a research report about the lives of adults with a Corpus Callosum disorder.<\/p>\n<p>Click <a href=\"https:\/\/doi.org\/10.1007\/s41252-023-00323-8\">here<\/a> to read a review of published literature about the cognitive and psychological impacts of CCD on adults.<\/p>\n<p>Click <a href=\"https:\/\/doi.org\/10.1007\/s11136-024-03741-w\">here<\/a> to read an article reporting on how the subjective well-being of adults with a Corpus Callosum disorder compares to that of the Australian population.<\/p>\n<\/p>\n<p>\n<\/div><\/div><\/div><\/div><\/div><\/section><section class=\"kc-elm kc-css-775164 kc_row\"><div class=\"kc-row-container  kc-container\"><div class=\"kc-wrap-columns\"><div class=\"kc-elm kc-css-871981 kc_col-sm-12 kc_column kc_col-sm-12\"><div class=\"kc-col-container\"><div class=\"kc-elm kc-css-371111 kc_shortcode kc_single_image\">\n\n        <img decoding=\"async\" src=\"http:\/\/ccd.brighterworld.biz\/dcc\/wp-content\/uploads\/4-DCC-IMAGES-copy.png\" class=\"\" alt=\"\" \/>    <\/div>\n<\/div><\/div><\/div><\/div><\/section><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","footnotes":""},"_links":{"self":[{"href":"http:\/\/ccd.brighterworld.biz\/dcc\/wp-json\/wp\/v2\/pages\/287"}],"collection":[{"href":"http:\/\/ccd.brighterworld.biz\/dcc\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/ccd.brighterworld.biz\/dcc\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/ccd.brighterworld.biz\/dcc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/ccd.brighterworld.biz\/dcc\/wp-json\/wp\/v2\/comments?post=287"}],"version-history":[{"count":39,"href":"http:\/\/ccd.brighterworld.biz\/dcc\/wp-json\/wp\/v2\/pages\/287\/revisions"}],"predecessor-version":[{"id":1117,"href":"http:\/\/ccd.brighterworld.biz\/dcc\/wp-json\/wp\/v2\/pages\/287\/revisions\/1117"}],"wp:attachment":[{"href":"http:\/\/ccd.brighterworld.biz\/dcc\/wp-json\/wp\/v2\/media?parent=287"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}